Assorbimento di alcune triazine simmetriche sulla frazione organica di un suolo bruno della Sardegna

The adsorption of four s-triazines on the A1-horizon of a brown soil from Sardinia was studied. The adsorption isotherms showed to be essentially linear. Prometryne, hydroxipropazine and prometone were highly absorbed at pH 5, scarcely at pH 2. Propazina behaved differently, showing the highest adsorption at low pH values. Adsorption was affected by the acidity of aqueous systems and tends to increase with a decrease in pH, reaching a maximum in the vicinity of the pK of the respective compounds

Assorbimento di alcune triazine simmetriche su una bentonite di Uri (Sardegna)

The adsorpition of six s-triazines of the chloro- and methoxy-analogue series on a bentonite from Uri (Sardinia) was studied. The H-bentonite shows a higher adsorption than the Na-bentonite. The order of adsorbabiIity of chloro-s-triazines was trietazine > atrazine > propazine; by me· thoxy-s-triazines it was simetone > atratone > prometone. The amount of simetone adsorbed by the H-bentonite occurred in excess of the CEC. The relationship between adsorption, solubility and lenght of the lateral chain of the s-triazine was confirmed. The adsorption was mainly due to van der Waals forces, H-bonding and ionic exchange

low enthalpy geothermal systems for air conditioning a case study in the mediterranean climate

Abstract This paper presents a preliminary evaluation of the technical and economic feasibility of a low-enthalpy geothermal system for air conditioning and its integration with other systems, including a photovoltaic plant and an electrical storage system. The pilot building is a research center located in the southern side of the Mediterranean basin (Sardinia, Italy). Preliminarily, the main geological, hydrogeological and geothermal characteristics of the area were analyzed. Then, an energetic assessment of the building and its plants was performed. The hourly production of a photovoltaic plant already designed for the building was assessed. To improve the energy efficiency and the thermal energy self-consumption, an alternative thermal generation plant was proposed to replace the existing air conditioning system: a water-water heat pump coupled with a low-enthalpy geothermal probe (vertical configuration), to be embedded into the ground or placed into an existing groundwater well. The feasibility of electric storage was evaluated by considering a system capacity of 100 kWh to temporarily store and self-consume the electricity overproduced by the photovoltaic plant. A preliminary economic assessment showed the viability of the photovoltaic system. The 100 kWh-capacity electric storage will increase the self-production percentage, but it is not economically affordable. The replacement of the current air-water heat pumps with one water-water heat pump will be economically convenient if coupled with a groundwater geothermal probe, but the solution of a vertical probe embedded into the ground is unsustainable, due to high drilling costs

Synergistic effects of fluticasone propionate and salmeterol on in vitro T-cell activation and apoptosis in asthma

In asthma T cells are characterized by an increased activation state and by reduced apoptosis

Fluorescence-guided lung nodule identification during minimally invasive lung resections

In the last few years, minimally invasive surgery has become the standard routine practice to manage lung nodules. Particularly in the case of robotic thoracic surgery, the identification of the lung nodules that do not surface on the visceral pleura could be challenging. Therefore, together with the evolution of surgical instruments to provide the best option in terms of invasiveness, lung nodule localization techniques should be improved to achieve the best outcomes in terms of safety and sensibility. In this review, we aim to overview all principal techniques used to detect the lung nodules that do not present the visceral pleura retraction. We investigate the accuracy of fluorescence guided thoracic surgery in nodule detection and the differences among the most common tracers used

Surgical and survival outcomes with perioperative or neoadjuvant immune-checkpoint inhibitors combined with platinum-based chemotherapy in resectable NSCLC: A systematic review and meta-analysis of randomised clinical trials

: The use of neoadjuvant or perioperative anti-PD(L)1 was recently tested in multiple clinical trials. We performed a systematic review and meta-analysis of randomised trials comparing neoadjuvant or perioperative chemoimmunotherapy to neoadjuvant chemotherapy in resectable NSCLC. Nine reports from 6 studies were included. Receipt of surgery was more frequent in the experimental arm (odds ratio, OR 1.39) as was pCR (OR 7.60). EFS was improved in the experimental arm (hazard ratio, HR 0.55) regardless of stage, histology, PD-L1 expression (PD-L1 negative, HR 0.74) and smoking exposure (never smokers, HR 0.67), as was OS (HR 0.67). Grade > = 3 treatment-related adverse events were more frequent in the experimental arm (OR 1.22). The experimental treatment improved surgical outcomes, pCR rates, EFS and OS in stage II-IIIB, EGFR/ALK negative resectable NSCLC; confirmatory evidence is warranted for stage IIIB tumours and with higher maturity of the OS endpoint

Hyperbaric exposure and oxidative Stress in occupational activities (HEOxS): the study protocol

Background: Hyperbaric exposure (HE) is proven to be a stressor to several mechanisms in living cells. Even if after homeostasis restoration, harmful effects are expected, in particular a presence of free radicals. These latter are the stimulus to negative phenomenon as inflammation or cancer. In Italy, with 7500 km of sea shores, a large quantity of workers is exposed to HE during occupational activities. A deep knowledge of HE and bodily effects is not well defined; hence a multidisciplinary assessment of risk is needed. To detect one or more indicators of HE a research group is organised, under the INAIL sponsorship. The research project focused on the oxidative stress (OxS) and this paper details on the possible protocol to estimate, with a large amount of techniques on several human liquids, the relationship between OxS and HE. Specific attention will be paid to identify confounding factors and their influence. Methods: Blood and urine will be sampled. Several lab techniques will be performed on samples, both targeted, to measure the level of well-known biomarkers, and untargeted. Regard the formers: products of oxidation of DNA and RNA in urine; inflammation and temperature cytokines and protein carbonyles in blood. Untargeted evaluation will be performed for a metabolomics analysis in urine. Confounding factors: temperature, body fat, fitness, allergies and dietary habits. These factors will be assessed, directly or indirectly, prior and after HE. The final scope of the project is to determine one or more indicators that relates to HE in hits twofold nature: depth and duration. Conclusion: The relationship between OxS and HE is not deeply investigated and literature proposes diverging results. The project aims to define the time dependence of biomarkers related to OxS, to rise knowledge in risk assessment in workers exposed to HE

Preliminary Characterization of the Digitally Formed Beams of PHAROS2 Phased Array Feed

We describe the beamforming strategy and the preliminary laboratory characterization results of the beam pattern synthesized by the PHAROS2 Phased Array Feed (PAF), a 4-8 GHz PAF with digital beamformer for radio astronomy application. The PAF is based on an array of 10×11 dual-polarization Vivaldi antennas cryogenically cooled at 20 K along with low noise amplification modules (LNAs) cascaded with a multi-channel Warm Section (WS) receiver. We present the beamforming and test procedures used to, respectively digitally synthesize and characterize the PHAROS2 antenna array beam pattern at 6 GHz. The tests of the array were carried out at room temperature by directly connecting 24 antenna elements to the WS and iTPM digital beamformer in a laboratory measurement setup